The rate of Estrogen receptors ,progesterone receptors and pidermal growth factor 2 receptors discordance between primary and recurrent breast cancer and its effect on survival

Background:Treatment of recurrent breast cancer, like treatment early-stage is based on consideration tumor biology and clinical history. Thus, characterization hormonal HER2 status critical for all patients, a detailed assessment past treatment, including timing therapies as well patient symptoms functional assessment, essential. Determination hormone receptor should be repeated in cases first recurrence when diagnostic tissue obtained because there may discordance between the primary tumors. Aim study: 1-To determine rate estrogen ,progestron epidermal growth factor2 (HER2) receptors cancer. 2-To study effect patient's disease free survival Patients method: The was conducted retrospectively included 100 Iraqi female patients attended Baghdad oncology teaching hospital January 2012 December 2017 whom , progesteron were known at time diagnosis had been new biopsy recurrence. Results: 1-The are 24%,27%,17% respectively 2-There not statistically significant difference concordant discordant both progestron while form increase factor 2 compared to ones. Conclusion:The ,while gain after associated with better survival.